What is the difference between arthritis medicines Mobic and Celebrex?

Question by rraytann: What is the difference between arthritis medicines Mobic and Celebrex?
I take 200 mg Celebrex every day for arthritis. My RN friend says she takes Mobic 15 mg and it is the only arthritis medicine her hospital prescribes since it is safer and works better than Celebrex. I want to know why it is safer and what, if any, are the side effects?

Chosen answer:

Answer by ckm1956
Celebrex is called a COX-2 type drug. There’s much less chance of stomach irritation than with other arthritis drugs.

I doubt seriously that Mobic is the only arthritis medicine your friend’s hospital uses. What if someone is allergic to it?

What it comes down to is that your doctor knows you better than your friend. Ask him/her at your next visit to answer your questions.


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2 Responses to “What is the difference between arthritis medicines Mobic and Celebrex?”

  1. quijibored says:

    Celebrex is classified as a COX 2 inhibitor used as a pain reliever. Mobic inhibits both COX 1 and COX 2. Both are used for arthritis.
    Simple explanation is that Mobic may be a bit stronger but more likely to cause stomach irritation. Less simple answer is whichever NSAID works best for you is your best choice. If the Celebrex is working ok, why change? If not, try another NSAID. There are many good choices available, assuming you don’t have ulcers or heart problems which contraindicate using either type NSAID (non steroidal anti inflammatory drug).

    http://www.fda.gov/cder/consumerinfo/druginfo/mobic.htm

    http://www.fda.gov/cder/drug/infopage/celebrex/celebrex-ptsk.htm

  2. sgunes says:

    About celebrex: It is true that it is slightly better for the stomach (GI tract in general) and it does not have the detrimental side effects (increased cardiovascular morbidity and mortality) that vioxx and bextra had.
    Mobic is a less specific COX-2 inhibitor and has never been shown to be any better than celebrex.
    As mobic is not generic it is as expensive as celebrex.
    If you are looking for a cheaper alternative to celebrex, I would recommend Etodolac as it is generic and overall better tolerated than ibuprofen or naprosyn.
    From a personal standpoint: my mother tolerated celebrex ok but had severe stomach problems with mobic. As always YMMV.
    Disclaimer: I am not a paid consultant for any of these companies and have no direct financial interest in them.

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