Piroxicam – Benefits, dosage, side effects

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Piroxicam is a nonsteroidal anti-inflammatory drug (NSAIDs) that serves to relieve pain. How NSAIDs work is to inhibit enzymes that produce prostaglandins, which are compounds released by the body and cause pain and inflammation.

Piroxicam is often used to reduce arthritis symptoms, such as inflammation, swelling, and muscle stiffness and pain. Please remember that piroxicam can only reduce symptoms, but does not cure arthritis.

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About Piroxicam

Types of nonsteroidal anti-inflammatory drugs
Prescription Drug Group
Benefits Relieve pain, inflammation, and fever
Consumed by adults
Forms of tablets, capsules, topical drugs
Categories of pregnancy and lactation
Category C: Drugs that are based on their pharmacological effects have been or are thought to be capable of adversely affecting the fetus, but not causing a permanent disability


  • Women who are planning a pregnancy, have fertility problems, or are pregnant (especially in the last trimester) are prohibited from taking piroxicam. While nursing mothers are advised to consult a doctor first before using this drug.
  • Do not take piroxicam over the dosage or duration recommended by your doctor.
  • If you take piroxicam, you should not drive or operate heavy equipment because this drug can cause drowsiness and dizziness.
  • Please be aware if you suffer from anemia, gastric ulcers, digestive disorders, asthma, allergies to other non-steroidal anti-inflammatory drugs (eg ibuprofen), diabetes, liver disorders, kidney disorders, heart disease, blood clots, edema, hyperkalemia, hypertension, dehydration, levels low sodium, and heart failure. Likewise with smokers and consuming liquor.
  • During using Piroxicam, tell your doctor before undergoing any medical treatment.
  • Ask about the dosage of children to the doctor.
  • If an allergic reaction or overdose occurs, see a doctor immediately.


The dose of piroxicam depends on the type of disease experienced, the severity of the symptoms, the condition of health, age, and the patient’s body response. The usual dose given to adult patients is 20 mg per day. The patient’s condition will then be reviewed by the doctor after 2 weeks of use. Especially for elderly patients, the use of piroxicam is only recommended with a minimum dose and duration.

While for the topical drug Piroxicam, patients are advised to use an ointment with a 0.5% piroxicam content 3 to 4 times a day. Monitoring will resume after 1 month of use.

Take Piroxicam correctly

Use piroxicam as instructed by the doctor and don’t forget to read the description on the packaging.

Piroxicam should be consumed with food. During taking this drug, patients are also advised to drink a lot to avoid dehydration and stop or reduce smoking and liquor so as to reduce the risk of bleeding in the stomach.

Skin that is more sensitive to light may also occur while using piroxicam. Therefore, patients are advised to wear closed hats or clothing while traveling.

Make sure there is enough time between one dose and the next. Try to consume piroxicam at the same time every day to maximize its effects.

For patients who forget to take piroxicam, it is recommended to do it immediately if paused with the next consumption schedule not too close. If it’s close, ignore it and don’t double the dose.

Piroxicam interactions and other drugs

There are a number of drugs that have the potential to cause unwanted reactions if taken together with Piroxicam. Some of them include:

  • Anticoagulants, aspirin, clopidogrel, corticosteroids, heparin, rivaroxaban, or serotonin selective release inhibitors (SSRIs); increases the risk of gastric bleeding.
  • Probenecid; increase the risk of piroxicam side effects.
  • Cholestyramine; decreases the effectiveness of piroxicam.
  • Bisphosphonates, cyclosporine, hydantoin, lithium, methotrexate, quinolone, sulfonamide, or sulfonylurea; because piroxicam has the potential to increase the side effects of these drugs.
  • ACE inhibitors or diuretics; because piroxicam can reduce the effectiveness of these drugs.

Recognize the Side Effects and Dangers of Piroxicam

All drugs have the potential to cause side effects, including piroxicam. Some of the common side effects when taking this medicine are:

  • Bloated.
  • Heartburn
  • Constipation or diarrhea.
  • Headache.
  • Nausea.
  • Gag.

Stop using the drug immediately and see a doctor if you experience serious side effects such as fever, difficulty breathing, shivering, dazed, headaches that don’t heal, convulsions, emotional changes, weakness, fatigue, changes in viewing ability, urine accompanied by blood, colored stools black or mixed with blood, and vomiting blood.

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