Cefoperazone – Benefits, dosage, side effects

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Cefoperazone is a cephalosporin antibiotic drug used to treat bacterial infections. Cefoperazone is available as an injection, which is only given by a doctor. As an antibiotic, this drug works by killing bacteria and suppressing the rate of development in the body. Keep in mind that antibiotics are only effective against bacteria, so they are not effective in dealing with viral infections, such as flu.

Trademarks: Biorazon, Cefoperazone, Cepraz, Corazon, Ferzobat, Logafox, Ozo, Sulpefion, Stabixin-1

About Cefoperazone

Cephalosporin antibiotic group
Prescription Drug Category
Benefits of treating bacterial infections.
Used by adults
Categories of pregnancy and lactation
Category B: Studies in experimental animals have not shown a risk to the fetus, but there are no controlled studies in pregnant women. It is not yet known whether cefoperazone is safe or not to be given to nursing mothers. Therefore, breastfeeding mothers are advised to consult a doctor first before using this medicine.
Form of injection


  • Giving cefoperazone for children and the elderly should only be done if recommended by a doctor.
  • Be careful when using this medicine if you have blood clotting disorders, impaired kidney function, intestinal diseases (for example ulcerative colitis), liver and bile disease, cystic fibrosis, impaired nutrient absorption (malabsorption), blood and urine sugar checks, or are getting nutrition from the infusion.
  • If you are allergic to penicillin or cephalosporin, you should be careful when using cefoperazone.
  • Tell your doctor if you are taking other drugs, including supplements and herbal products.
  • If an allergic reaction or overdose occurs, see a doctor immediately.

Cefoperazone dose

To deal with bacterial infections that attack adults, the injection dose of cefoperazone given by the doctor is 2-4 grams per day, which is divided into 2 times. In severe infections, the dose can be increased to 12 grams per day, which is divided into 2-4 times.

Using Cefoperazone correctly

It is not recommended to use cefoperazone injections without supervision from a doctor or medical officer. Regular health checks are also recommended to help doctors monitor the progress of the disease condition and the effectiveness of the drug.

Be sure to complete the medication dosage the doctor recommends, even though the infection feels better. This is to ensure the infection-causing bacteria are destroyed while preventing infections from recurring.

Drug Interactions

Avoid using the following drugs along with cefoperazone to prevent unwanted interactions:

  • Aminoglycosides and furosemide – increase the risk of kidney disorders.
  • Anticoagulants – increase the risk of bleeding.

Recognize the Side Effects and Dangers of Cefoperazone

Side effects that may arise after using this drug are:

  • Cough
  • Hard to breathe
  • Fever
  • Shivering
  • The body feels weak and tired
  • Nausea
  • Dark urine
  • Pain when urinating
  • Heartbeat
  • Back pain.

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